[vc_row padding_top=”60″ padding_bottom=”10″][vc_column][vc_custom_heading text=”Medication Considerations” use_theme_fonts=”yes” letter_spacing=””][/vc_column][/vc_row][vc_row padding_top=”10″ padding_bottom=”60″][vc_column width=”2/3″][vc_column_text css=”” letter_spacing=””]Ibogaine has a complicated and multifaceted mechanism of action. This means that it can interact with various kinds of medications and certain precautions have to be observed prior to treatment. For individuals evaluating timing, preparation, and ibogaine treatment costs, understanding how medications may impact treatment is an important part of the process. Below is a general outline of the types of medications and our basic pre-treatment protocols, however for the most accurate recommendations we will ask you to thoroughly outline your prescription and non-prescription drug use in the application process.[/vc_column_text][vc_tta_accordion][vc_tta_section title=”Short-Acting Opioids (heroin, oxycontin, etc.)” tab_id=”1548493366283-bc4cbc1c-d508″][vc_column_text letter_spacing=””]We do not require a period of abstinence prior to arriving at the center. Abstinence or the lowest possible dose is optimal for treatment preparation, however the most important priority is that your dose is stable and comfortable. Stability is all that we stress during the intake process. We stabilize with morphine sulfate or similar medication upon arrival.[/vc_column_text][/vc_tta_section][vc_tta_section title=”Long-Acting Opioids (methadone, buprenorphine)” tab_id=”1548493366320-99cc6a93-5756″][vc_column_text letter_spacing=””]For long-acting opioids such as methadone and buprenorphine we require patients to switch to short acting opioids prior to arrival.
- For methadone, we require a minimum of 15-20 days.
- For buprenorphine-based medications, we require a minimum of 35-50 days.
[/vc_column_text][/vc_tta_section][vc_tta_section title=”Stimulants (cocaine, crack, methamphetamine, MDMA, ritalin/aderal, caffeine)” tab_id=”1548493821891-b31b3600-394d”][vc_column_text letter_spacing=””]Stimulants can interact with ibogaine in a number of ways, from prolonging the QT interval (cocaine/crack, methamphetamine), affecting CYP2D6 metabolism (methamphetamine), or simply because of ibogaine’s potential interaction with their acute and residual effects.
- For cocaine and crack we require a minimum of 7 days abstinence.
- For other stimulants such as methamphetamine, MDMA, or prescription stimulants like Ritallin or Adderall, we require 5 days abstinence prior to treatment.
- For coffee we also recommend a period of 5 days abstience prior to treatment.
[/vc_column_text][/vc_tta_section][vc_tta_section title=”Alcohol” tab_id=”1548493864280-239e494d-a2d7″][vc_column_text letter_spacing=””]We recommend that all patients refrain from drinking alcohol for at least 3 days before ibogaine administration, and for at least a week afterwards.
We require that patients who are at risk for alcohol withdrawal syndrome, and specifically for seizures during withdrawal, be completely detoxed from alcohol dependency under medical supervision for 5 to 7 days prior to treatment.[/vc_column_text][/vc_tta_section][vc_tta_section title=”Benzodiazepines” tab_id=”1548493892589-a1bf0f21-d40d”][vc_column_text letter_spacing=””]Benzodiazepines affect the GABAnergic neurotransmitter system on which ibogaine has no effect. Ibogaine does not reduce withdrawal symptoms associated with benzodiazepines, and actually could pose some potential risks, such as ampliflying the risk of seizures during withdrawal. Seizures during the ibogaine experience an lead to dangerous cardiac arrhyhtmias that require medical intervention.
It is extremely important that patients report any benzodiazepine use within the past 3 months.
For patients who are physically dependent on benzodiazepines and who are pursuing treatment for other reasons, such as opioid dependence, we require that the dose be stabilized prior and continued throughout the ibogaine treatment process.
Detoxification from benzodiazepines can require a long-term slow taper. For more information, please refer to the Ashton Manual.[/vc_column_text][/vc_tta_section][vc_tta_section title=”QT prolonging medications, foods and supplements” tab_id=”1548493911886-0d73c6f1-4722″][vc_column_text letter_spacing=””]Ibogaine causes bradycardia, hypotension, and prolongation of the QT interval. Each of these symptoms may be in conjunction with or independent of the others. Other QT prolonging drugs exacerbate these effects, which can put a patient at greater risk for lethal cardiac arrhythmias.
We assess the potential interaction of any other QT prolonging medication on a case-by-base basis.[/vc_column_text][/vc_tta_section][vc_tta_section title=”CYP2D6 Affecting Medications” tab_id=”1548493928215-b5c825a7-0347″][vc_column_text letter_spacing=””]CYP2D6 is the enzyme by which ibogaine is metabolized in the liver. Other medications that affect CYP2D6 metabolism could have an impact on treatment.
We assess the potential interaction of any and all CYP2D6 affective drug on a case-by-case basis.[/vc_column_text][/vc_tta_section][vc_tta_section title=”Serotonin Increasing-Medications” tab_id=”1548494930222-3e18452a-475b”][vc_column_text letter_spacing=””]Ibogaine can increase serotonin levels in the body, and in conjunction with other medications that have the same action can lead to serotonin syndrome with symptoms of acute confusional state.
Examples of these medications include, but are not limited to SSRIs, SNRIs, NRIs, MAOIs, buspirone (anxiety tx), trazodone (depression & insomnia tx), certain migraine medications, certain pain medications (fentanyl, meperidine, pentazocine and tramadol), dextromethorphan (cough suppressant), certain anti-nausea medications (granisetron, metoclopramide, ondansetron), cocaine, and some dietary supplements like St. John’s Wort.
We require that patients be off of these medications and stable for at least 7 days prior to treatment.[/vc_column_text][/vc_tta_section][vc_tta_section title=”Monoamine oxidase inhibitors (MAOIs)” tab_id=”1548495879845-22ca3302-119a”][vc_column_text letter_spacing=””]MAOIs affect the metabolism of many different drugs. They are infrequently used as anti-depressants, but may still form part of regimens for Parkinsons disease, and are a constituent part of ayahuasca.
We require that patients refrain from the use of MAOIs for at least 7 days prior to arrival.[/vc_column_text][/vc_tta_section][vc_tta_section title=”Calcium Channel Blockers or Beta Blockers” tab_id=”1548496837584-81d26040-cfde”][vc_column_text letter_spacing=””]These medications can lower blood pressure and heart rate dramatically, and alter electrical conduction through the heart. However, there may be concern about the underlying conditions that these medications are meant to treat and the cardiac effects of ibogaine.
We consider the potential interactions of these drugs on a case-by-base basis.[/vc_column_text][/vc_tta_section][vc_tta_section title=”Centrally Acting Drugs” tab_id=”1548494511062-93e45344-df02″][vc_column_text letter_spacing=””]Because of many possible and sometimes poorly understood interactions with ibogaine and certain centrally acting medications, we may recommend that any non-essential medications be paused prior to treatment.
This can include certain non-essential blood pressure medications, non-benzodiazepine hypnotics (i.e. Z class drugs), barbiturates, muscle relaxants, antipsychotics, anticonvulsants and general anesthetics.[/vc_column_text][/vc_tta_section][vc_tta_section title=”Diuretics” tab_id=”1548494500790-0bbc7c76-92cb”][vc_column_text letter_spacing=””]Diuretics can lead to a reduction of certain key electrolytes. We generally require the discontinuation of diuretic medication prior to conducting intake lab tests for accurate pre-treatment readings.[/vc_column_text][/vc_tta_section][/vc_tta_accordion][/vc_column][vc_column width=”1/3″][vc_single_image image=”730″ img_size=”full” alignment=”center” style=”vc_box_circle_2″][/vc_column][/vc_row][vc_row text_align=”center” text_color=”#ffffff” type=”color” bg_color=”#1c110a”][vc_column width=”3/4″][vc_custom_heading text=”Are You Ready to Take the First Step?” font_container=”tag:h3|text_align:center” use_theme_fonts=”yes” letter_spacing=””][/vc_column][vc_column width=”1/4″][kleo_button title=”Apply Now” href=”https://anzelmoibogaine.com/ibogaine-treatment/application” style=”highlight” position=”left” size=”lg” icon=”0″ letter_spacing=””][/vc_column][/vc_row][vc_row padding_top=”60″ padding_bottom=”10″][vc_column][vc_custom_heading text=”Medical Screening” use_theme_fonts=”yes” letter_spacing=””][/vc_column][/vc_row][vc_row padding_top=”10″][vc_column width=”2/3″][vc_column_text css=”” letter_spacing=””]Upon arriving at the Anzelmo there are a number of medical tests that we require to screen you for treatment. These include:
- 12-lead Electrocardiogram (or further cardiac testing if necessary)
- Full blood panel
- Urine drug test
These tests are conducted in order to ensure the safety of your ibogaine treatment. If you have concerns about any of these tests and want to have them conducted and screened prior to arrival, or if you already have access to an ECG or blood panel, after speaking with an intake counselor, please send for review. They will be conducted again upon arrival for verification.
Depending on the results of the screening tests Anzelmo reserves the right to deny treatment (and offer a full refund of the deposit minus the cost of medical care received), to delay treatment, or to prescribe a preparation protocol prior to treatment.
For many clients traveling for ibogaine treatment in Mexico, this screening process provides additional clarity before arrival and helps reduce avoidable complications. It also helps inform next steps beyond treatment, including recommendations for aftercare and recovery coaching to support long-term stability.
In some cases, applicants are also navigating long-standing stress, anxiety, or symptoms related to PTSD, making accurate screening and honest disclosure especially important prior to treatment.[/vc_column_text][/vc_column][vc_column width=”1/3″][vc_separator color=”custom” style=”dashed” accent_color=”#ebae5d”][vc_custom_heading text=”Read More: Is Ibogaine Treatment Safe?” font_container=”tag:h4|text_align:center” use_theme_fonts=”yes” letter_spacing=”” link=”url:https%3A%2F%2Fanzelmoibogaine.com%2Fwhat-is-ibogaine%2Fis-ibogaine-treatment-safe||target:%20_blank|”][/vc_column][/vc_row][vc_row content_placement=”middle” text_align=”center” text_color=”#444444″ type=”color” bg_color=”#faf7ef” vertical_align=”yes” inline_style=”border-top: 1px solid #ebae5d;”][vc_column width=”2/3″][vc_custom_heading text=”Have Any Additional Questions?” font_container=”tag:h3|text_align:center” use_theme_fonts=”yes” letter_spacing=””][/vc_column][vc_column width=”1/3″][kleo_button title=”Contact Us” href=”https://anzelmoibogaine.com/contact-us” style=”highlight” position=”left” size=”lg” icon=”0″ letter_spacing=””][/vc_column][/vc_row]